After many sessions testing Lossless in both TSW and TSC, I have come to the conclusion it is not of any real value to me. It seems to cause the occassional crash, makes Alt-Tabbing between windows problematic, does not work for remote play. In scaling mode, any upscaling results in blurry text such as in gauges. In other cases, switching between scaled mode and unscaled mode, I can't tell the difference.

So I staying with TSW with Jetwash's mods - his medium settings with game screen settings on high (not ultra) and I get 50 to 60 frame rate most of the time.